Host: Rabbit

Target Protein: GLRB

IR: Immunogen Range:51-150/497

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 2743

Swiss Prot: P48167

Source: KLH conjugated synthetic peptide derived from human GLRB:51-150/497 

Purification: affinity purified by Protein A

Storage: Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: GLRB (Glycine receptor beta) is a neurotransmitter-gated ion channel concentrated within the spinal cord and brainstem. Expression is also observed in several upper brain regions including the cortex, cerebellum, hippocampus and amygdala. Binding of glycine to GLRB increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing), controlling spinal reflexes and locomotor behavior.