Host: Rabbit
Target Protein: CD68
IR: Immunogen Range:111-210/335
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 12514
Swiss Prot: P31996
Source:
KLH conjugated synthetic peptide derived from mouse CD68:111-210/335
Purification: affinity purified by Protein A
Storage: Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008].
Size: 100ul
Concentration: 1mg/ml
Applications: Flow-Cyt=3ug/Test, ELISA=1:5000-10000
Cross Reactive Species: Human (predicted: Mouse,Rat)
For research use only. Not intended for diagnostic or therapeutic use.