Host: Rabbit
Target Protein: SerpinB6
IR: Immunogen Range:131-230/376
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 5269
Swiss Prot: P35237
Source: KLH conjugated synthetic peptide derived from human SerpinB6:131-230/376
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: The protein encoded by this gene is a member of the serpin (serine proteinase inhibitor) superfamily, and ovalbumin(ov)-serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog was found to be expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress, and that loss of this protection results in cell death and sensorineural hearing loss. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2010]
Size: 200ul
Concentration: 1mg/ml
Applications: WB=1:500-2000
Cross Reactive Species: (predicted: Human,Mouse,Monkey)
For research use only. Not intended for diagnostic or therapeutic use.