Host: Rabbit

Target Protein: NLRC3

IR: Immunogen Range:721-820/1065

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 197358

Swiss Prot: Q7RTR2

Source: KLH conjugated synthetic peptide derived from human NLRC3:721-820/1065 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: This gene encodes a NOD-like receptor family member. The encoded protein is a cytosolic regulator of innate immunity. This protein directly interacts with stimulator of interferon genes (STING), to prevent its proper trafficking, resulting in disruption of STING-dependent activation of the innate immune response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]