Host: Rabbit
Target Protein: MX2
IR: Immunogen Range:621-715/715
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 4600
Swiss Prot: P20592
Source: KLH conjugated synthetic peptide derived from human MX2:621-715/715
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: Members of the Dynamin family include GTPase, microtubule-associated proteins that are involved in cellular trafficking, including microtubule bundling and endocytosis. Mx1, also known as MxA, an interferon (IFN)-induced protein, acquires a high degree of resistance to influenza A virus and the rhabdo-virus vesicular stomatitis virus (VSV), which suggests that Mx1 plays an active role against influenza virus and the rhabdovirus VSV. Mx1 is a cytoplasmic protein that is 63% identical to the Mx2 protein, which lacks antiviral activity. Mx2 is also known as MxB and is localized at the cytoplasmic face of nuclear pores. Mx2 expression is not interferon-dependent and this protein is thought to regulate the efficiency and/or kinetics of nuclear import, a function which may have been usurped by its antiviral relatives.
Size: 100ul
Concentration: 1mg/ml
Applications: IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:25, IF=1:100-500, ELISA=1:5000-10000
Cross Reactive Species: Human
For research use only. Not intended for diagnostic or therapeutic use.