Host: Rabbit

Target Protein: Beta-arrestin 2

IR: Immunogen Range:251-350/409

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 409

Swiss Prot: P32121

Source: KLH conjugated synthetic peptide derived from human Beta-arrestin 2:251-350/409 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: Members of arrestin/beta arrestin protein family are thought to participate in agonist mediated desensitization of G protein coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors