Host: Rabbit

Target Protein: phospho-MAPK15 (Thr175 + Tyr177)

IR: Immunogen Range:AV(p-T)E(p-Y)VA

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 225689

Swiss Prot: Q8TD08

Source: KLH conjugated synthesised phosphopeptide derived from human MAPK15 around the phosphorylation site of Thr175 + Tyr177:AV(p-T)E(p-Y)VA 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: MAPK15 is a 544 amino acid protein that belongs to the CMGC Ser/Thr protein kinase family (MAP kinase subfamily). MAP kinases play a significant role in many biological processes, including cell adhesion and spreading, cell differentiation and apoptosis. MAPK15 functions as a catalytic kinase using ATP to produce ADP and a phosphoprotein. A TXY motif, containing one threonine and one tyrosine residue, activates the MAP kinases upon phosphorylation. MAPK15 is a ubiquitously expressed protein with highest expression found in lung and kidney.