Host: Rabbit

Target Protein: IER3IP1

IR: Immunogen Range:21-60/82

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 51124

Swiss Prot: Q9Y5U9

Source: KLH conjugated synthetic peptide derived from human IER3IP1:21-60/82 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: IER3IP1 has a G-patch domain which is thought to function in the binding of RNA. The G-patch domain is associated with various proteins which exhibit functions which may include tumor suppression and DNA damage repair, suggesting that IER3IP1 may be involved in cellular responses to DNA damage. Matrine is a molecule that induces erythroid cell differentiation of K562 cells and the presence of the IER3IP1 gene is thought to increase matrine function, implying a possible role for IER3IP1 in erythroid cell differentiation.