Host: Rabbit
Target Protein: MTHFD1
IR: Immunogen Range:51-150/935
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 4522
Swiss Prot: P11586
Source: KLH conjugated synthetic peptide derived from human MTHFD1:51-150/935
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: This gene encodes a protein that possesses three distinct enzymatic activities, 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase. Each of these activities catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses. The trifunctional enzymatic activities are conferred by two major domains, an aminoterminal portion containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain. [provided by RefSeq, Jul 2008]
Size: 100ul
Concentration: 1mg/ml
Applications: IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500
Cross Reactive Species: (predicted: Human,Mouse,Rat,Cow,Xenopus laevis, Orangutan)
For research use only. Not intended for diagnostic or therapeutic use.