Host: Rabbit

Target Protein: KK-LC-1/CT83

IR: Immunogen Range:51-113/113

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 203413

Swiss Prot: Q5H943

Source: KLH conjugated synthetic peptide derived from human KK-LC-1/CT83:51-113/113 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: The X and Y chromosomes are the human sex chromosomes. Chromosome X consists of about 153 million base pairs and nearly 1,000 genes. The combination of an X and Y chromosome lead to normal male development while two copies of X lead to normal female development. There are a number of conditions related to an unsual number and combination of sex chromosomes being inherited. More than one copy of the X chromosome with a Y chromosome causes Klinefelter's syndrome. A single copy of X alone leads to Turner's syndrome. More than 2 copies of the X chromosome, in the absence of a Y chromosome, is known as Triple X syndrome. Color blindness, hemophilia, and Duchenne muscular dystrophy are well known X chromosome-linked conditions which affect males more frequently as males carry a single X chromosome. The KK-LC-1 gene product has been provisionally designated KK-LC-1 pending further characterization.