Host: Rabbit
Target Protein: CDHR4
IR: Immunogen Range:501-600/788
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 389118
Swiss Prot: A6H8M9
Source:
KLH conjugated synthetic peptide derived from human CDH29:501-600/788
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: The cadherins are a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. Cadherin-29, also known as Cadherin-related family member 4, is a 788 amino acid single-pass type I membrane protein that has four cadherin domains. There are two isoforms of cadherin-29 that are produced as a result of alternative splicing events. The gene encoding cadherin-29 maps to human chromosome 3, which is is made up of about 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells.
Size: 50ul
Concentration: 1mg/ml
Applications: IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
Cross Reactive Species: (predicted: Human,Mouse,Pig,Horse)
For research use only. Not intended for diagnostic or therapeutic use.