bs-10170R [Primary Antibody]
Rabbit  Anti-FLT3L Rabbit pAb  Polyclonal Antibody
www.bioss.com.cn
sales@bioss.com.cn
techsupport@bioss.com.cn
400-901-9800
DATASHEET

Host: Rabbit

Target Protein: FLT3L Rabbit pAb

IR: Immunogen Range:61-160/235

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 2323

Swiss Prot: P49771

Source: KLH conjugated synthetic peptide derived from human FLT3L:61-160/235 

Purification: affinity purified by Protein A

Storage: 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

Background: Flt 3 ligand (Flt 3-L), variously designated Flt 3/Flk 2 ligand or FL, is a hematopoietic growth factor that stimulates the proliferation of stem and CD34+ progenitor cells and has been cloned from both mouse and human genomes. Flt 3-L is a potent in vitro growth stimulator of granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-3 (IL-3), and G-CSF-dependent granulocyte-macrophage committed precursors from Lin CD34+ bone marrow cells as well as other primitive B cell populations. Additionally, Flt 3-L stimulates the proliferation of hematopoietic progenitor cells isolated from mouse fetal liver or adult mouse bone marrow. Flt 3-L does not, however, affect the growth of erythroid-committed progenitors. Flt 3-L exists in two forms and is active as both a soluble and as a membrane-bound ligand. The Flt 3-L receptor, Flt 3, is a tyrosine kinase expressed on CD34+ cells that shares a high degree of homology with the SCF (stem cell factor) receptor, c-Kit and c-Fms.

Size: 200ul

Concentration: 1mg/ml

Applications: WB=1:500-2000

Cross Reactive Species: Human,Mouse (predicted: Rat,Pig,Cow,Dog,Horse)

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES
Sample: intestine (Mouse) Lysate at 40 ug Primary: Anti-FLT3L(bs-10196R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 23 kD Observed band size: 28 kD
 
PRODUCT SPECIFIC PUBLICATIONS