Host: Rabbit

Target Protein: Phospho-c-Fos (Ser374)

IR: Immunogen Range:LS(p-S)PT

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 2353

Swiss Prot: P01100

Source: KLH conjugated Synthesised phosphopeptide derived from human c-Fos around the phosphorylation site of Ser374:LS(p-S)PT 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. [provided by RefSeq, Jul 2008].