Host: Rabbit
Target Protein: CTLA4
IR: Immunogen Range:75-170/223
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 1493
Swiss Prot: P16410
Source:
KLH conjugated synthetic peptide derived from human CTLA-4/CD152:75-170/223
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.
Size: 200ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, Flow-Cyt=1μg/Test, ELISA=1:5000-10000
Cross Reactive Species: Rat,Mouse,Human (predicted: Sheep,Rabbit,Cow,Dog)
For research use only. Not intended for diagnostic or therapeutic use.