Host: Rabbit
Target Protein: AES
IR: Immunogen Range:21-120/197
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 166
Swiss Prot: Q08117
Source: KLH conjugated synthetic peptide derived from human TLE5/Amino-terminal enhancer of split:21-120/197
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: TLE5 is a 197 amino acid nuclear protein that belongs to the TLE family. Expressed predominately in fetal brain, liver, lung, heart and kidney and in adult muscle, TLE5 functions as either a homooligomer or a heterooligomer with other TLE family members and, through this association, dominantly represses the expression of TLE genes. In addition, TLE5 can repress NFkB-regulated gene expression and is thought to play an important role in initiating and maintaining cell differentiation events. Two isoforms of TLE5 exist due to alternative splicing events.
Size: 50ul
Concentration: 1mg/ml
Applications: ELISA=1:5000-10000
Cross Reactive Species: (predicted: Human,Mouse,Rat,Chicken,Cow,Sheep)
For research use only. Not intended for diagnostic or therapeutic use.