Host: Rabbit
Target Protein: 5HT2A Receptor
IR: Immunogen Range:51-150/471
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 3356
Swiss Prot: P28223
Source:
KLH conjugated synthetic peptide derived from human 5HT2A Receptor:51-150/471
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Size: 50ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, IHC-F=1:100-500, IF=1:100-500, ELISA=1:5000-10000
Cross Reactive Species: Human,Mouse,Rat (predicted: Dog,Pig,Cow,Horse,Sheep)
For research use only. Not intended for diagnostic or therapeutic use.