bs-10021R [Primary Antibody]
Rabbit  Anti-NALP3/CIAS1  Polyclonal Antibody
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Host: Rabbit

Target Protein: NALP3/CIAS1

IR: Immunogen Range:15-120/1036

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 114548

Swiss Prot: Q96P20

Source: KLH conjugated synthetic peptide derived from human Cryopyrin:15-120/1036 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: May function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65. Also inhibits transcriptional activity of RELA. Activates caspase-1 in response to a number of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18.

Size: 50ul

Concentration: 1mg/ml

Applications: WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:200-800, Flow-Cyt=2ug/Test, ELISA=1:5000-10000

Cross Reactive Species: Human,Mouse,Rat,Dog

For research use only. Not intended for diagnostic or therapeutic use.

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