Host: Rabbit
Target Protein: ZDHHC-18
IR: Immunogen Range:265-360/388
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 84243
Swiss Prot: Q9NUE0
Source: KLH conjugated synthetic peptide derived from human ZDHHC-18:265-360/388
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZDHHC1 (zinc finger, DHHC-type containing 1), also known as ZNF377 (zinc finger protein 377) or C16orf1, is a 485 amino acid multi-pass membrane protein that contains one DHHC-type zinc finger. Expressed in fetal heart, lung and kidney and also present in adult lung and pancreas, ZDHHC1 functions as a palmitoyltransferase that catalyzes the conversion of palmitoyl-CoA and protein-cysteine to S-palmitoyl protein and CoA. Like ZDHHC1, ZDHHC5, ZDHHC6, ZDHHC7 and ZDHHC18 each contain one DHHC-type zinc finger through which they convey palmitoyltransferase activity against a broad range of substrates, including H-Ras, SNAP 25 and GABAA R proteins.
Size: 100ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, ELISA=1:5000-10000
Cross Reactive Species: Mouse (predicted: Human,Rat,Chicken,Dog,Pig,Cow,Horse)
For research use only. Not intended for diagnostic or therapeutic use.