Host: Rabbit

Target Protein: PTBP1

IR: Immunogen Range:451-531/531

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 5725

Swiss Prot: P26599

Source: KLH conjugated synthetic peptide derived from human PTBP1:451-531/531 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA.