Host: Rabbit

Target Protein: TEM1

IR: Immunogen Range:251-350/757

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 57124

Swiss Prot: Q9HCU0

Source: KLH conjugated synthetic peptide derived from human TEM 1:251-350/757 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: The transmembrane glycoprotein Tumor endothelial marker 1 (TEM1) is highly expressed in tumor endothelial cells however it is barely detectable on normal endothelial cells. It is believed to play a role in tumor angiogenesis. It is expressed in stromal fibroblasts, metastatic hepatic lesions and during angiogenesis of corpus luteum formation and wound healing. TEM1 is being investigated as a potential target for cancer treatment.