Host: Rabbit

Target Protein: IL-17RD

IR: Immunogen Range:401-500/739

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 54756

Swiss Prot: Q8NFM7

Source: KLH conjugated synthetic peptide derived from human IL-17RD:401-500/739 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: Feedback inhibitor of fibroblast growth factor mediated Ras-MAPK signaling and ERK activation. May inhibit FGF-induced FGFR1 tyrosine phosphorylation. Regulates the nuclear ERK signaling pathway by spatially blocking nuclear translocation of activated ERK without inhibiting cytoplasmic phosphorylation of ERK. Mediates JNK activation and may be involved in apoptosis.