Host: Rabbit
Target Protein: stabilin1
IR: Immunogen Range:1201-1400/2570
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 23166
Swiss Prot: Q9NY15
Source:
KLH conjugated synthetic peptide derived from human stabilin1:1201-1400/2570
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: Stabilin-1 is a large transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 16 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to endocytose ligands such as low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein rapidly cycles between the plasma membrane and early endosomes.
Size: 100ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, ELISA=1:5000-10000
Cross Reactive Species: Mouse (predicted: Human,Rat,Cow,Horse)
For research use only. Not intended for diagnostic or therapeutic use.