Host: Rabbit

Target Protein: phospho-PAK2 (Ser141) Rabbit pAb

IR: Immunogen Range:YM(p-S)FT

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 5062

Swiss Prot: Q13177

Source: KLH conjugated Synthesised phosphopeptide derived from human PAK2 around the phosphorylation site of Ser141:YM(p-S)FT 

Purification: affinity purified by Protein A

Storage: 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

Background: The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. [provided by RefSeq, Jul 2008]