Host: Rabbit
Target Protein: phospho-PAK2 (Ser141) Rabbit pAb
IR: Immunogen Range:YM(p-S)FT
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 5062
Swiss Prot: Q13177
Source: KLH conjugated Synthesised phosphopeptide derived from human PAK2 around the phosphorylation site of Ser141:YM(p-S)FT
Purification: affinity purified by Protein A
Storage: 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background: The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. [provided by RefSeq, Jul 2008]
Size: 200ul
Concentration: 1mg/ml
Applications: IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
Cross Reactive Species: Mouse (predicted: Human,Rat,Rabbit,Cow,Dog,Horse)
For research use only. Not intended for diagnostic or therapeutic use.