Host: Rabbit
Target Protein: phospho-ERK1 (Thr202/Tyr204) + ERK2 (Thr183/Tyr185)
IR: Immunogen Range:FL(p-T)E(p-Y)VA
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 5595
Swiss Prot: P28482
Source: KLH conjugated Synthesised phosphopeptide derived from mouse ERK1/2 around the phosphorylation site of Thr202/Tyr204:FL(p-T)E(p-Y)VA
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.
Size: 100ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, Flow-Cyt=1μg /test, ELISA=1:5000-10000
Cross Reactive Species: Rat,Mouse,Human (predicted: GuineaPig,Rabbit,Horse,Cow,Dog,Chicken)
For research use only. Not intended for diagnostic or therapeutic use.