Host: Rabbit
Target Protein: OCLN
IR: Immunogen Range:431-522/522
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 18260
Swiss Prot: Q61146
Source:
KLH conjugated synthetic peptide derived from mouse OCLN:431-522/522
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. [provided by RefSeq, Apr 2011]
Size: 100ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, Flow-Cyt=2µg/Test, ELISA=1:5000-10000
Cross Reactive Species: Human (predicted: Mouse,Rat,Dog,Pig,Cow,Horse,GuineaPig)
For research use only. Not intended for diagnostic or therapeutic use.