Host: Rabbit

Target Protein: Jagged1

IR: Immunogen Range:1101-1218/1218

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 182

Swiss Prot: P78504

Source: KLH conjugated synthetic peptide derived from human CD339:1101-1218/1218 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq].