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Host: Rabbit
Target Protein: MTNR1B Rabbit pAb
IR: Immunogen Range:201-300/362
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 4544
Swiss Prot: P49286
Source:
KLH conjugated synthetic peptide derived from human MTNR1B:201-300/362
Purification: affinity purified by Protein A
Storage: 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background: This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.
Size: 50ul
Concentration: 1mg/ml
Applications: WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
Cross Reactive Species: Human,Mouse
For research use only. Not intended for diagnostic or therapeutic use.
