Host: Rabbit
Target Protein: CD86
IR: Immunogen Range:
Clonality:
Isotype: IgG
Entrez Gene: 942
Swiss Prot: P42081
Source: KLH conjugated synthetic peptide derived from human CD86:
Purification: affinity purified by Protein A
Storage: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011].
Size: 50ul
Concentration: 1mg/ml
Applications: WB=1:200-2000, IHC-P=1:100-500, ICC=1:100, IF=1:20-200
Cross Reactive Species: Human (predicted: Rat)
For research use only. Not intended for diagnostic or therapeutic use.