Host: Rabbit
Target Protein: ADAM17
IR: Immunogen Range:141-240/824
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 6868
Swiss Prot: P78536
Source: KLH conjugated synthetic peptide derived from human ADAM17:141-240/824
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway. [provided by RefSeq].
Size: 200ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, ELISA=1:5000-10000
Cross Reactive Species: Human (predicted: Sheep,Rabbit,Horse,Cow,Pig,Dog,Rat,Mouse)
For research use only. Not intended for diagnostic or therapeutic use.