Host: Mouse

Target Protein: Occludin

IR: Immunogen Range:

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 100506658

Swiss Prot: Q16625

Source: KLH conjugated synthetic peptide derived from human Occludin: 

Purification: affinity purified by Protein A

Storage: PBS, Glycerol, BSA Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. [provided by RefSeq, Apr 2011]