Host: Mouse
Target Protein: MUC16
IR: Immunogen Range:12660-12923/14507
Clonality: Monoclonal
Isotype: IgG
Entrez Gene: 94025
Swiss Prot: Q8WXI7
Source: Recombinant human MUC16 Protein:12660-12923/14507
Purification: affinity purified by Protein A
Storage: Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: MUC16 (CA125) is a serum marker that is used routinely in gynecologic practice to monitor patients with ovarian cancer. It is a mullerian duct differentiation antigen that is overexpressed in epithelial ovarian cancer cells and secreted into the blood, although its expression is not entirely confined to ovarian cancer. Most biochemical studies have concluded that MUC16 is a high molecular mass glycoprotein, although estimates of its size range from 200 to 2000 kDa with smaller “subunits” being described by some investigators.
Size: 50ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, ELISA=1:5000-10000
Cross Reactive Species: Human
For research use only. Not intended for diagnostic or therapeutic use.