Host: Rabbit
Target Protein: Periostin
IR: Immunogen Range:
Clonality:
Isotype: IgG
Entrez Gene: 10631
Swiss Prot: Q15063
Source: KLH conjugated synthetic peptide derived from human Periostin:
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background: Periostin is a disulfide linked 90 kDa, 811 amino acid protein originally isolated as a osteoblast-specific factor that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading. Additionally, periostin expression has previously been shown to be significantly increased by both transforming growth factor beta 1(TGF beta 1) and bone morphogenetic protein (BMP2). Periostin has a typical signal sequence, followed by a cysteine-rich domain, a fourfold repeated domain and a C-terminal domain. The fourfold repeated domain of OSF2 shows homology with the insect protein fasciclin. Periostin mRNA is expressed in the developing mouse embryonic and fetal heart, and that it is localized to the endocardial cushions that ultimately divide the primitive heart tube into a four-chambered heart. Abnormal expression of periostin is also linked to angiogenesis and metastatsis in epithelial tumors.
Size: 100ul
Concentration: 1mg/ml
Applications: WB=1:200-1000, IHC-P=1:100-500, Flow-Cyt=1:20-100
Cross Reactive Species: (predicted: Human)
For research use only. Not intended for diagnostic or therapeutic use.