Host: Rabbit
Target Protein: CD3E
IR: Immunogen Range:23-120/189
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 12501
Swiss Prot: P22646
Source:
KLH conjugated synthetic peptide derived from mouse CD3 epsilon:23-120/189
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008].
Size: 100ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, IHC-P=1:100-500, IF=1:100-500, ELISA=1:5000-10000
Cross Reactive Species: Human,Mouse (predicted: Rat)
For research use only. Not intended for diagnostic or therapeutic use.