Host: Rabbit

Target Protein: Nogo B

IR: Immunogen Range:251-357/357

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 57142

Swiss Prot: Q9NQC3

Source: KLH conjugated synthetic peptide derived from human RTN4 isoform B:251-357/357 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The product of this gene is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified.