Host: Rabbit

Target Protein: Alpha 2 antiplasmin

IR: Immunogen Range:161-260/491

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 5345

Swiss Prot: P08697

Source: KLH conjugated synthetic peptide derived from human SERPINF2:161-260/491 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: Alpha 2 Antiplasmin is a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene.