Host: Mouse

Target Protein: GFAP(ready to use)

IR: Immunogen Range:

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 2670

Swiss Prot: P14136

Source: Recombinant mouse GFAP full length,: 

Purification: affinity purified by Protein A

Storage: 0.01M PBS (pH7.4) with 1% BSA and 0.02% Proclin300. Store at 2-8℃ for one year. Avoid repeated freeze/thaw cycles.

Background: Glial fibrillary acidic protein (GFAP) is an intermediate filament (IF) protein that is expressed by numerous cell types of the central nervous system (CNS) including astrocytes and ependymal cells during development. GFAP has also been found to be expressed in glomeruli and peritubular fibroblasts taken from rat kidneys Leydig cells of the testis in both hamsters and humans, human keratinocytes, human osteocytes and chondrocytes and stellate cells of the pancreas and liver in rats. It is closely related to its non-epithelial family members, vimentin, desmin, and peripherin, which are all involved in the structure and function of the cell’s cytoskeleton. GFAP is thought to help to maintain astrocyte mechanical strength, as well as the shape of cells but its exact function remains poorly understood, despite the number of studies using it as a cell marker.