Host: Rabbit
Target Protein: Jagged 2
IR: Immunogen Range:201-300/1238
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 3714
Swiss Prot: Q9Y219
Source:
KLH conjugated synthetic peptide derived from human Jagged 2:201-300/1238
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: Jagged 2 is a Notch ligand involved in the mediation of Notch signaling. Jagged 2 is expressed in heart, placenta and skeletal muscle and to a lesser extend in pancreas. Very low expression in brain, lung, liver and kidney. The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. Jagged 2 is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for Jagged 2.
Size: 50ul
Concentration: 1mg/ml
Applications: WB=1:500-2000,IHC-P=1:100-500,ELISA=1:5000-10000
Cross Reactive Species: Human (predicted: Mouse,Rat,Pig,Cow,Dog)
For research use only. Not intended for diagnostic or therapeutic use.