Host: Rabbit

Target Protein: WIPI2/Atg21

IR: Immunogen Range:181-280/454

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 26100

Swiss Prot: Q9Y4P8

Source: KLH conjugated synthetic peptide derived from human WIPI2/Atg21:181-280/454 

Purification: affinity purified by Protein A

Storage: 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

Background: WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI2, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al., 2004 [PubMed 15602573]).[supplied by OMIM, Mar 2008]