Host: Rabbit
Target Protein: RANK
IR: Immunogen Range:101-200/616
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 8792
Swiss Prot: Q9Y6Q6
Source:
KLH conjugated synthetic peptide derived from human RANK/CD265:101-200/616
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Aug 2012]
Size: 50ul
Concentration: 1mg/ml
Applications: WB=1:500-2000,ELISA=1:5000-10000
Cross Reactive Species: Human (predicted: Mouse,Rabbit,Sheep)
For research use only. Not intended for diagnostic or therapeutic use.