Host: Rabbit
Target Protein: GPAA1
IR: Immunogen Range:301-400/621
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 8733
Swiss Prot: O43292
Source: KLH conjugated synthetic peptide derived from human GPAA1:301-400/621
Purification: affinity purified by Protein A
Storage: 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background: Glycosylphosphatidylinositol (GPI) acts as a membrane anchor for cell surface proteins. Glycosylphosphatidylinositol anchor attachment 1 protein (GPAA1), also designated GPI anchor attachment protein 1 or GAA1 protein homolog, is a membrane protein localized to the endoplasmic reticulum which is involved in GPI-anchor biosynthesis. GPAA1 is crucial for GPI-anchoring of precursor proteins and catalyzes the attachment of GPI to proteins containing a C-terminal GPR attachment signal. GAA1 contains an N-terminal signal sequence, one cAMP- and cGMP-dependent protein kinase phosphorylation site, two potential N-glycosylation sites, one leucine zipper pattern and eight putative transmembrane domains. GPAA1 is ubiquitously expressed and shows higher levels of expression in fetal tissues than in adult tissues.
Size: 50ul
Concentration: 1mg/ml
Applications: ELISA=1:5000-10000
Cross Reactive Species: (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow)
For research use only. Not intended for diagnostic or therapeutic use.