Host: Rabbit
Target Protein: Phospho-TIE2 (Tyr1108)
IR: Immunogen Range:TL(p-Y)EK
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 7010
Swiss Prot: Q02763
Source: KLH conjugated Synthesised phosphopeptide derived from human TIE2 around the phosphorylation site of Tyr1108:TL(p-Y)EK
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis.TEK is closely related to the TIE receptor tyrosine kinase.
Size: 50ul
Concentration: 1mg/ml
Applications: WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
Cross Reactive Species: Human,Mouse,Rat (predicted: Rabbit,Pig,Sheep,Cow,Chicken,Dog,Horse)
For research use only. Not intended for diagnostic or therapeutic use.