Host: Rabbit

Target Protein: SPA-1

IR: Immunogen Range:351-450/1042

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 6494

Swiss Prot: Q96FS4

Source: KLH conjugated synthetic peptide derived from human SPA-1:351-450/1042 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date.