Host: Mouse
Target Protein: human CD3/AF750
IR: Immunogen Range:
Clonality: Monoclonal
Isotype: Mouse IgG2a, k
Entrez Gene: 916
Swiss Prot: P07766
Source: :
Purification: Affinity purified by Protein G
Storage: 0.01M PBS, 0.5%BSA, 0.03% Proclin300 Store at 2-8℃. Protect from light. Avoid freezing.
Background: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]
Size: 50T
Concentration:
Applications:
Cross Reactive Species:
For research use only. Not intended for diagnostic or therapeutic use.