Host: Rabbit
Target Protein: SNCA
IR: Immunogen Range:51-90/140
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 6622
Swiss Prot: P37840
Source: KLH conjugated synthetic peptide derived from human alpha-Synuclein:51-90/140
Purification: affinity purified by Protein A
Storage: 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background: Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016].
Size: 200ul
Concentration: 1mg/ml
Applications: WB=1:500-2000,ELISA=1:5000-10000
Cross Reactive Species: Human,Mouse,Rat (predicted: Pig,Cow,Chicken)
For research use only. Not intended for diagnostic or therapeutic use.