Host: Rabbit
Target Protein: alpha + beta Synuclein
IR: Immunogen Range:32-44/140
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 6620
Swiss Prot: P37840
Source: KLH conjugated synthetic peptide derived from human alpha + beta Synuclein:32-44/140
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: Synucleins are small soluble proteins expressed primarily in neural tissues and in certain tumors. The family includes 3 known proteins, alpha synuclein, beta synuclein and gamma synuclein. All synucleins have in common a highly conserved alpha helical lipid binding motif with similarity to the class A2 lipid binding domains of the exchangeable apolipoproteins. The alpha and beta synuclein proteins are found primarily in brain tissue, where they are seen mainly in pre synaptic terminals. Alpha synuclein is believed to be a major component of Lewy bodies in Parkinson’s disease. Mutations in alpha synuclein are associated with rare familial cases of early onset Parkinson’s disease, Alzheimer’s disease and several other neurodegenerative illnesses.
Size: 200ul
Concentration: 1mg/ml
Applications: IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
Cross Reactive Species: Human,Mouse,Rat,Zebrafish (predicted: Rabbit,Pig,Cow,Chicken,Dog)
For research use only. Not intended for diagnostic or therapeutic use.