Host: Rabbit
Target Protein: HDAC1
IR: Immunogen Range:381-482/482
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 3065
Swiss Prot: Q13547
Source: KLH conjugated synthetic peptide derived from human HDAC1:381-482/482
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008]
Size: 200ul
Concentration: 1mg/ml
Applications: WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,Flow-Cyt=1:50-300,IF=1:100-500,ELISA=1:5000-10000
Cross Reactive Species: Human,Mouse,GuineaPig (predicted: Rat,Pig,Sheep,Cow,Dog)
For research use only. Not intended for diagnostic or therapeutic use.