Host: Rabbit
Target Protein: BMPER
IR: Immunogen Range:501-600/686
Clonality: Polyclonal
Isotype:
Entrez Gene: 168667
Swiss Prot: Q8N8U9
Source: KLH conjugated synthetic peptide derived from human BMPER:501-600/686
Purification: affinity purified by Protein A
Storage: 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background:
This gene encodes a secreted protein that interacts with, and inhibits bone morphogenetic protein (BMP) function. It has been shown to inhibit BMP2- and BMP4-dependent osteoblast differentiation and BMP-dependent differentiation of the chondrogenic cells. Mutations in this gene are associated with a lethal skeletal disorder, diaphanospondylodysostosis. [provided by RefSeq, Dec 2011].
BMPER is a BMP-binding protein that is expressed by endothelial cell precursors, has BMP-antagonizing activity, and may play a role in endothelial cell differentiation by modulating local BMP activity. It may also regulate BMP responsiveness in osteoblasts and chondrocytes.
Size: 100ul
Concentration: 1mg/ml
Applications: WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
Cross Reactive Species: Human,Mouse,Rat (predicted: Rabbit,Pig,Cow,Dog)
For research use only. Not intended for diagnostic or therapeutic use.