Host: Mouse
Target Protein: CSF1R
IR: Immunogen Range:
Clonality: Monoclonal
Isotype: IgG1
Entrez Gene: 1436
Swiss Prot: P07333
Source: KLH conjugated synthetic peptide derived from human CSF1R/CD115:
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: This protein tyrosine kinase transmembrane receptor is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a member of the CSF1/PDGF receptor family of tyrosine protein kinases and contains 5 immunoglobulin like C2 type domains. CD115 is expressed by cells of the monocytic lineage and by progenitor cells. Mutations in this gene have been associated with a predisposition to myeloid malignancy.
Size: 100ul
Concentration: 1mg/ml
Applications: WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:20-50,IF=1:20-50
Cross Reactive Species: (predicted: Human)
For research use only. Not intended for diagnostic or therapeutic use.