Host: Rabbit
Target Protein: PRNP
IR: Immunogen Range:23-120/253
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 5621
Swiss Prot: P04156
Source: KLH conjugated synthetic peptide derived from human PRNP:23-120/253
Purification: affinity purified by Protein A
Storage: 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background: The function of PrP is still under debate. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis (By similarity). Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).
Size: 100ul
Concentration: 1mg/ml
Applications: IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
Cross Reactive Species: (predicted: Human,Mouse,Rat,Cow,Horse)
For research use only. Not intended for diagnostic or therapeutic use.