Host: Mouse

Target Protein: Mart-1

IR: Immunogen Range:

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 2315

Swiss Prot: Q16655

Source: KLH conjugated synthetic peptide derived from human Mart-1: 

Purification: affinity purified by Protein A

Storage: PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: Melan A, a product of the MART-1 gene, is a melanocyte differentiation marker recognized by autologous cytotoxic T lymphocytes. Other melanoma-associated markers recognized by autologous cytotoxic T cells are reported to include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1 and GAGE-1. The analysis of these different molecules and their expression in individual melanomas may be of help in the study of their particular molecular roles in melanocyte differentiation and tumorigenesis.